Clenbuterol: Ultimate Guide for Men & Women

Dr George TouliatosDisclaimer: The following article is for educational purposes only and NOT to promote the use of illegal substances. If you have any questions or concerns, Dr. Touliatos is currently available for consultations.

Clenbuterol is a β2-adrenoceptor agonist and bronchodilator, formulated to treat various breathing disorders, such as: inflammatory airway disease (IAD) and recurrent airway obstruction (RAO).

Clenbuterol is an effective anti-asthma medication, having been an approved prescription drug for humans since 1977 in several countries (albeit not the US).

In research, we have seen clenbuterol demonstrate strong anabolic effects in animals; significantly increasing skeletal muscle mass, whilst reducing fat (1).

This has led to bodybuilders purchasing clenbuterol on the black market and utilizing it in cutting cycles, alongside other fat-burning steroids.

Hollywood celebrities have also been known to cycle clenbuterol, in attempts to transform their bodies in a short space of time.

However, we have found clenbuterol’s effects in humans to be somewhat dissimilar to those in animals. Clenbuterol’s ability to burn fat is undisputed; however, its muscle-building effects in humans are questionable.

Some users report no anabolic effects from clenbuterol, whereas others are adamant about its ability to add lean muscle tissue.

The truth may lie somewhere in the middle, with clenbuterol having anabolic properties; although not to the degree of anabolic-androgenic steroids.

Thus, clenbuterol may help bodybuilders retain muscle when cutting, although significant increases in muscle size and strength are unlikely in our experience. This is therefore more of an anti-catabolic effect (rather than anabolic).

Clenbuterol is generally taken as an oral; however, it is also available as a syrup or injection.

Legal Clenbuterol Alternative

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Clenbutrol is our #1 rated legal clenbuterol product. It replicates the fat burning and thermogenic effects of clenbuterol, but without any unwanted side effects.

It is FDA approved and can be purchased online without a prescription.

Clenbutrol is best suited for men or women who want to reduce their body fat percentage, whilst simultaneously increasing muscle tone and endurance.

Clenbuterol Benefits

  • Fat loss
  • Increased Blood Flow
  • Enhanced Energy
  • Appetite Suppression
  • Diuretic
  • No testosterone Suppression

Fat Loss

Clenbuterol stimulates the central nervous system (CNS), thus increasing adrenaline output and raising the body’s temperature by as much as 1 degree.

Consequently, in an attempt to maintain homeostasis, the body stimulates the sweat glands to cool itself back down to its previous temperature.

This constant ‘cooling effect’ increases total calorie expenditure, thus spiking a user’s basil metabolic rate.

Thus, we find users will typically burn more calories at rest than usual.

This makes it easier for bodybuilders to eat in a calorie deficit and burn fat indirectly (due to an elevated metabolism).

However, clenbuterol also has direct fat-burning effects (similar to other beta-2 agonists), by accelerating the conversion of triglycerides to free fatty acids.

Increased Blood Flow

Clenbuterol increases adrenaline levels, thus shifting the body into fight or flight mode. Consequently, blood flow improves throughout the body as a survival mechanism.

Thus, we have seen clenbuterol improve muscular endurance, enabling bodybuilders to perform more repetitions than usual (in less time).

Note: if a person’s blood pressure or heart rate rises excessively, endurance may suffer on Clenbuterol, thus this benefit is dependent on the person and how they react to clenbuterol.

Pumps can also become bigger, due to superior blood circulation to the muscles.

Bigger pumps and increased reps, may indirectly help to build new muscle; due to stretching of the muscle fascia.

Fascia is a connective tissue that surrounds the muscles; however, if too tight, muscle growth can be inhibited.

As the a muscle tries to expand, it effectively is pushing against the deep fascia. Therefore, the more flexible this tissue becomes, the greater potential for muscle hypertrophy.

Bigger pumps from clenbuterol will aid in helping your fascia become more supple, reducing such friction.

Users also report accelerated recovery after workouts and requiring less sleep than usual.

Note: When a person remains in fight or flight mode for an extended period of time, cortisol levels can rise excessively, with vasoconstriction occurring. This impairs blood flow and increases fatigue; which may occur in the latter stages of a clenbuterol cycle, following the initial increase in blood flow.

Enhanced Energy

Pre-workouts are popular due to stimulants being present in their formulas, such as caffeine; giving users intense workouts.

Stimulants arouse the central nervous system; causing the body to release more adrenaline, providing a substantial burst in energy.

Clenbuterol is a powerful stimulant, more so than any standard pre-workout, thus energy levels will go through the roof.

However, what goes up must come down. Thus, we find users commonly experiencing a crash with low energy after this initial effect wears off; consequently creating a dependence on clenbuterol.

High energy levels on clenbuterol can also (indirectly) help to burn more fat; due to workouts becoming more intense. For example, you may perform HIIT on a stationary bike for 15 minutes; however, on clenbuterol you may be able to comfortably extend this to 20+ minutes.

Appetite Suppression

Clenbuterol has a stimulating effect on beta 2-angrenergic receptors, which can affect satiety levels in humans.

Consequently, our patients have reported not feeling as hungry throughout the day; despite burning more calories.

This effect can indirectly assist with further fat loss, due to users being less likely to cave in and binge eat their favourite high-calorie foods.

This is very beneficial to someone who struggles to ‘diet’, as users will naturally feel fuller for longer periods on clenbuterol; causing them to naturally eat smaller portions.


Clenbuterol doesn’t just burn fat but also flushes out extracellular water. This can result in a person looking visibly leaner and having increased muscle tone.

We attribute clenbuterol’s diuretic effects to the amount of sweating that occurs.

Therefore, it is important to drink adequate levels of water on clen, as you lose sodium via your sweat which can lead to dehydration and muscle cramps.

Any water lost from taking clenbuterol will return post-cycle, making this diuretic effect temporary. 

No Testosterone Suppression

One of the biggest drawbacks we see with anabolic steroids is the shutting down of natural testosterone production.

Typically after a steroid cycle, it can take several weeks or months for endogenous testosterone to return back to normal levels.

However, clenbuterol (unlike anabolic steroids) does not compromise your testosterone. Thus, no PCT is needed and you don’t need to worry about losing your results.

Legal Steroid Alternatives That Work

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Crazy Bulk's formulas are supported with clinical research and are safe for men and women to use.

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Clenbuterol Side Effects

  • Increased heart rate (palpitations)
  • Anxiety (shakes)
  • Insomnia

Increased Heart Rate

Clenbuterol arouses the sympathetic nervous system, causing users’ resting heart rate to become excessively elevated.

Dr. Thomas O’Connor also has anecdotal evidence of clenbuterol contributing to heart rates of 180 beats per minute.

We once had a patient experience chronic atrial fibrillation following clenbuterol use (2), a form of irregular heartbeat; caused by permanent cardiac scarring.

Thus, clenbuterol is an especially dangerous drug for anyone with existing heart issues or high blood pressure.


Anxiety is a common side effect of taking clenbuterol, due to its tendency to shift a person into fight or flight mode. Excessive arousal of the central nervous system may cause a person to perceive everyday situations as threats, negatively affecting their mental health.

A racing heart and palpitations may also trigger anxiety, as users may think they are having a heart attack.

Taking a sedative may help to calm the central nervous system and reduce anxiety levels. However, we have seen this counteract the thermogenic effect of clenbuterol; thus negatively affecting fat loss due to less adrenaline and heat production.

High levels of CNS stimulation are linked to depression, due to the subsequent ‘come down’ effect. This is due to clenbuterol initially boosting dopamine levels in the brain (3); for them later to drop, as a person builds tolerance or comes off the drug.

Shaking is also common when taking clenbuterol, due to greater adrenaline output. In our experience, this side effect mainly affects the hands.


Insomnia is common among clenbuterol-users, due to an overly active nervous system, causing hyperactivity (4).

Some bodybuilders suggest taking clenbuterol earlier in the day to improve the chances of falling asleep at night. However, clenbuterol has a very long half-life of 35 hours (5). Thus, we have found this protocol to be ineffective, with high amounts of clenbuterol still peaking in the bloodstream.

It is worth noting that sleep deprivation may elevate cortisol levels, further increasing blood pressure and inhibiting fat burning.

Clenbuterol Dosage

A person’s dosage will depend on what they are using clenbuterol for.

For example, an asthmatic may take 2 x 20mcg pills per day.

Patients suffering more severely from respiratory issues may take 4 x 20mcg pills per day.

However, bodybuilders or anyone taking clenbuterol for weight loss purposes may take 6-8 pills per day (120-160mcg). Such dosages are well beyond the therapeutic range used in medicine, therefore more severe side effects are to be expected.

People respond to potent stimulants differently, thus the dosage should be tailored to how sensitive a person is to the drug.

Unlike with anabolic steroids, the dosage of clenbuterol is the same for men and women. This is due to it affecting the CNS, rather than working on a hormonal level (where women have significantly less testosterone and thus need smaller doses of steroids to obtain the same level of results).

Clenbuterol Cycle

The following cycle is taken by men and women, who covet maximum fat loss and high levels of muscle definition.

clenbuterol cycle

We find users typically build a tolerance to clenbuterol quickly; thus to prolong its positive effects, users can start on a lower dosage and increase it slowly every third day.

A person should only continue increasing the dosage until the maximum amount, IF they are comfortable with the side effects. We have had patients complete a 30 day clenbuterol cycle, comfortably reaching a peak dose of 120mcg. However, we have also had patients report severe side effects on 80mcg/day (and thus have to cut their cycle short).

The reason why clenbuterol cycles typically do not last beyond 4-6 weeks is due to beta-receptor downregulation.

Thus, clenbuterol’s positive effects can only be experienced for a limited time, until the body successfully regulates its temperature back to normal; causing fat burning to come to a halt.

This is also why some users choose to cycle clenbuterol for 2 weeks on, followed by 2 weeks off; or 2 days on/2 days off.

2 Week On/Off Clenbuterol Cycle

As previously mentioned, a short clenbuterol cycle can be utilized to prevent the body from building up a tolerance to the drug, ensuring further fat loss in future cycles.

We have found that a 2 week cycle can also reduce cardiovascular strain, among other side effects.

In one journal, a healthy 25-year-old man was rushed to the ER after taking 20mcg of clenbuterol (6). His heart rate reached 140 beats per minute, whilst also displaying labile blood pressure.

He experienced palpitations, nausea, chest pain, sweating and anxiety.

Interestingly, he had been taking the same dose for the last 3 weeks, with no adverse effects. This is a prime example of how a 2 week cycle can be more optimal for sensitive users.

A 2 week cycle will often start in the 20-40mcg range, with the dose increasing every 1 or 2 days, until a maximum dose is achieved (usually being 100mcg-140mcg).

Users will then have 2 weeks of rest before cycling clenbuterol again. However, the second cycle begins with the maximum dose from the first cycle. Thus, if the first cycle finished on 100mcg per day, this would be taken for the entire 2 weeks in the second cycle.

Every follow up cycle from this point onwards should then start at the maximum dose to continue making progress.

Clenbuterol and Winstrol Cycle

For Men

clenbuterol winstrol cycle

Winstrol is an anabolic steroid, often utilized during cutting cycles, to enhance fat loss and lean muscle mass.

The addition of winstrol will have a more anabolic effect than taking clenbuterol alone. Thus, a person will build muscle and burn fat simultaneously on this stack; as opposed to predominantly burning fat with clenbuterol.

The side effects of winstrol are much different from clenbuterol. Winstrol is an oral like clen, however, it is highly hepatotoxic. Our liver function tests often show high ALT/AST enzymes in winstrol-users, indicating significant strain on the liver.

LDL cholesterol levels will also rise, causing a large spike in blood pressure. Hair loss, prostate enlargement and acne are other possible androgenic side effects we see, due to high DHT levels.

Winstrol will also cause endogenous testosterone production to shut down, taking several months for levels to recover back to normal (hence how bodybuilders opt for a post cycle therapy).

For Women

Winstrol generally is not a recommended steroid for women, due to high chances of virilization occurring. Such masculine effects however may be kept at bay by adopting a low dosage (as shown below).

clenbuterol winstrol cycle for women

There is generally no need to utilize this cycle (as a female) if the primary goal is fat loss. We find this can be achieved solely by dieting and taking clenbuterol. However, if more muscle tone and size are required; some women may run these two compounds together.

Clenbuterol and Anavar Cycle

For Men

clenbuterol anavar cycle for men

Anavar (oxandrolone) is regarded as a cutting steroid, due to its potent effects on fat loss.

Anavar also builds lean muscle and strength, making it ideal for users wanting to get bigger and stronger.

We regard anavar as slightly less powerful than winstrol in terms of results, yet a lot more side effect friendly. Anavar is an FDA-approved steroid in medicine and thus is generally regarded as safe by the bodybuilding community.

For Women

clenbuterol anavar cycle for women

Anavar, unlike winstrol, is a lot more suitable for women; due to low incidents of masculinization.

A clenbuterol and anavar cycle is taken by women wanting to look lean and strong; as opposed to slim.

Thus, female celebrities are likely to take clenbuterol alone; whereas athletes or serious weight lifters may add anavar.

Clenbuterol and Cytomel (T3) Cycle

Clenbuterol can also be stacked with Cytomel (T3) to enhance fat burning. Cytomel is a prescription medication for hypothyroidism (an underactive thyroid).

Simply put, the higher a person’s T3 levels are, the greater the rate of lipolysis (fat burning) in the body.

This stack is considered the ultimate fat-burning duo among bodybuilders looking to get ripped before a competition; however, it is not free from harsh side effects.

Users often take 25-75mcg of Cytomel per day, for 6-8 weeks.

50mcg is the standard dose for intermediate bodybuilders.

However, bodybuilders will often stack Cytomel with testosterone or another anabolic steroid; due to Cytomel’s catabolic effects on muscle tissue.

Clenbuterol Results (Before and After Pictures)

clenbuterol before and after

The user (above) cycled clenbuterol for 2 weeks, starting with a 20mg dose and slowly increasing up to 80mg/day.

This was the user’s first clenbuterol cycle, hence such impressive results.

We see a person’s results on clen often determined by the dosage, length of cycle, genetics, diet and workout routines.

For maximum fat loss, users should eat in a 500-calorie deficit. Clenbuterol’s metabolic effects will effectively be blunted if a person eats in a calorie surplus.

In our experience, men and women can expect to lose 10-15lbs from a 4 week cycle of clenbuterol.

Similarly to steroids, the more clenbuterol cycles a person performs, the less fat loss they will experience with each one. 

Legal Steroid Alternatives That Work

before after picture

Crazy Bulk is our recommended source for legal steroid alternatives, based on thousands of positive reviews on verified platforms, such as Trustpilot and Feefo.

Dr. Thomas O'Connor, head of our medical team, states: "There is evidence, if you could use these (steroid alternatives) they would be much better than using anabolic steroids".

Crazy Bulk's formulas are supported with clinical research and are safe for men and women to use.

legal steroids

A PCT isn’t needed with any of these products, as they do not suppress users’ natural testosterone production. Women can also take these legal steroid alternatives, as they do not cause virilization symptoms; unlike anabolic-androgenic steroids.

In short, clenbutrol is a much safer version of clenbuterol and will not cause an athlete to fail a drugs test.

Clenbutrol Reviews (Before and After Pictures)

clenbuterol results

Balwinder’s results from taking clenbutrol for 5 weeks

legal clenbuterol before and after

John Miller’s results from taking CB’s cutting stack (including clenbutrol) for 8 weeks

clenbuterol review

Kim lost 8lbs after taking clenbutrol, anvarol and winsol for 1 month. She lost 2 inches on her waist and 2.5 inches on her hips.


Clenbuterol vs Albuterol

Albuterol sulfate (also referred to as salbutamol), is a beta-2 adrenergic agonist, like clenbuterol.

The main difference however is that Albuterol is FDA-approved and an available prescription drug for the treatment of asthma.

Albuterol also burns fat through the process of thermogenesis, via the stimulation of the CNS. Thus, the benefits and side effects of albuterol are largely the same as clenbuterol.

However, albuterol is not as potent as clenbuterol, being regarded as a ‘cleaner stimulant’.

Consequently, albuterol’s side effects are more tolerable, being more cardiovascular-friendly.

However, the results on albuterol are less in our experience, with fat loss and energy levels being more noticeable on clenbuterol.

Albuterol also has a shorter half-life than clenbuterol, being 4-6 hours, thus requiring more frequent doses (3-4x per day).

Albuterol is administered via the same method as clenbuterol (in pill form). However, in medicine, albuterol is prescribed in the form of an emergency inhaler.

Is Clenbuterol Legal?

Yes, clenbuterol is technically legal in the US and other countries, as it is not listed in the Controlled Substances Act.

However, it is not approved by the FDA, thus users should be aware of its potentially damaging side effects.

Clenbuterol is also on the WADA banned list of substances, thus athletes can still fail a drugs test and be suspended (if found lingering in their system).

Is Clenbuterol Safe?

The FDA has not approved clenbuterol for human use, which is an indicator of its toxic nature. 

The Peking Union Medical College in Beijing, China, concluded that clenbuterol only had mild effects when given to rabbits (7).

However, when higher doses were administered; their heart rates increased drastically; inducing severe hypotension.

Thus, research suggests that clenbuterol’s safety may be dose-dependent (8). Anecdotally, we have also found higher dosages to be unsafe in regard to cardiotoxicity.

Note: Men and women with existing heart issues are at great risk when taking clenbuterol (irrespective of the dose). Also, if users are stacking clenbuterol with anabolic steroids, cardiac-related side effects will be exacerbated (9).

Is Weight Loss From Clenbuterol Permanent?

Yes, all results from clenbuterol are permanent and will not be reversed post-cycle.

However, a person must continue training and eating correctly if they want to maintain their results.

Note: Water loss is the only temporary effect, therefore users may regain a small amount of fluid when they finish their cycle.

Does Clenbuterol Work?

Yes; clenbuterol not only works, but is arguably the most potent fat burner in the world today.

However, it is bought on the black market where supplements are often tainted (10); thus it is difficult to know if you are getting 100% real, authentic clenbuterol.

clenbuterol bottle
As a general rule, if you are not experiencing fat loss, or feeling your body temperature rise — it is not clenbuterol.

However, it is worth noting that clenbuterol is not a compound typically counterfeited (possibly due to its low market price). Although it still occurs. 

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