Author Archive

Dr. Thomas O'Connor, MD, PA

Dr. O'Connor has over 20 years of experience treating men and women with a history of anabolic steroid, SARM, and PED use. He has been a board-certified MD since 2005 and provides guidance on harm reduction methodologies.

Dr. O'Connor is a clinical instructor at the University of Connecticut School of Medicine and has been featured in various media publications, including Generation Iron, Dr. Phil, National Geographic, The New York Times, Muscle and Fitness, and others.

Dr. O'Connor also co-authored the largest survey on anabolic steroid use, involving 2,385 men, published in the peer-reviewed American Journal of Men’s Health.

This article will address overtraining and whether it’s a legitimate concern for bodybuilders or if its effects have been sensationalized. There is a common belief in bodybuilding that if you train a muscle too long or too many times (without adequate rest days), you will enter a state of overtraining. Overtraining is a catabolic state caused by […]

As a potential medical treatment for cachexia, researchers developed selective androgen receptor modulators (SARMs) to mimic the muscle-building effects of anabolic steroids. Thus, SARMs’ main function is to increase anabolism. SARMs possess lipolytic properties due to stimulation of androgen receptors. We find that most SARMs can reduce overall body fat by 2–3% from a standard […]

SARMs (selective androgen receptor modulators) have recently been formulated as a potential medicinal alternative to anabolic steroids. Scientists’ main objective when synthesizing SARMs was to replicate the anabolic effects of steroids without any androgenic side effects. This has been successfully achieved via the mechanism of tissue selectivity, where SARMs bind to cells that promote anabolism […]

Summary: The best SARM for beginners with the fewest side effects is widely regarded as Ostarine. The best SARM for building lean muscle is believed to be RAD 140. The best SARM for cutting and burning fat could be Ostarine. However, Cardarine is a more effective fat-burning compound, but it is technically a peroxisome proliferator-activated […]

Non-steroidal selective androgen receptor modulators (SARMs) have become more common in the realm of bodybuilding since their recent formulation in the 1990s. Are SARMs Legal? As of 2022, SARMs are currently 100% legal worldwide (excluding Australia), when utilized for research purposes. In Australia, SARMs are classified as Schedule 4 substances, so they are illegal to […]