Ostarine for Women: The Ultimate Guide

Dr George TouliatosDisclaimer: SARMs are only to be used for research purposes, as they are non-FDA-approved compounds and thus may cause adverse effects. If you have any questions or concerns, Dr. Touliatos is currently available for consultation.

Ostarine (MK-2866) is a SARM taken by men and women in bodybuilding to enhance muscle building and fat burning. Athletes may also use Ostarine to increase muscular strength and power without causing excessive weight gain or extracellular water retention.

Ostarine Benefits for Women

Muscle Gain

The benefits of Ostarine for women are essentially the same as the benefits for men. However, certain effects are more amplified and promising in women, such as the level of muscle gain.

We have found that women can gain exceptional amounts of muscle on Ostarine, compared to only modest increases in men.

One female user had gained approximately 25 lbs from an Ostarine-only cycle, with a dosage starting at 7 mg/day and ending at 15 mg/day (1). She also reported keeping all of her results.

In contrast, men commonly report gaining only 5–10 pounds of lean muscle.

This anabolic effect may be more pronounced in women due to their having only a fraction (5%) of the testosterone of men. Thus, when Ostarine binds to the androgen receptor with tissue selectivity, enabling significant increases in free testosterone, women are more susceptible to higher spikes in protein synthesis and positive nitrogen retention within the muscle cells.

Therefore, as men already have roughly 20 times more endogenous testosterone than women, their potential for muscle hypertrophy is less.

Strength Gains

The strength gains from Ostarine are exceptional for both men and women, with increases of 30 pounds on main compound lifts being common during a first cycle.

Women will also notice being able to exercise for longer and with more intensity. Consequently, Ostarine users’ workouts will often increase in duration (consciously or subconsciously).

Also, muscle recovery will greatly improve, with DOMS (delayed onset muscle soreness) being experienced considerably less—if at all.

Fat Loss

In our experience, Ostarine’s muscle-building effects far outweigh its lipolytic (fat-burning) effects in both men and women.

However, Ostarine’s ability to reduce subcutaneous and visceral fat mass has resulted in it being utilized in cutting cycles as well as bulking ones.

Our tests show that Ostarine has a positive effect on insulin sensitivity, which is contrary to many other PEDs. Ostarine thus causes notable improvements in muscle definition in the abdominals (for women who are already lean).


Some women struggle with low energy, fatigue, and a lack of motivation, particularly when they experience estrogen dominance.

Ostarine significantly increases free testosterone, causing the opposite reactions to occur and improving overall well-being due to free testosterone stimulating dopamine receptors.

We find a woman’s results on Ostarine are largely determined by her past experience (or lack thereof) on PEDs. For example, a natural woman who takes Ostarine for the first time will have significantly better results compared to a woman who has cycled SARMs or Anavar for years. However, certain benefits, such as energy, motivation, and mood, can be experienced in their entirety with each cycle.

Disclosure: We do not accept any form of advertising on Inside Bodybuilding. We monetize our practice via doctor consultations and carefully chosen supplement recommendations, which have given our patients excellent results.

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Ostarine Side Effects in Women

Many women can take Ostarine and notice zero side effects from their cycle. This is the common outcome for women who take sensible dosages and adhere to standard cycle protocols.

Other women can experience hair thinning, acne, or even clitoral hypertrophy from Ostarine. However, these women often take very high dosages or run excessively long cycles.

Sex Drive

Fluctuations in sex drive are typically the main side effects women experience on Ostarine.

Thus, on-cycle, a woman’s libido can be greatly amplified, which may be advantageous or disadvantageous depending on the user. If this becomes an issue, women can reduce their dosage, which will lessen their sex drive.

Women are likely to be more sensitive (physiologically) to Ostarine, particularly in their breast and vaginal areas.

Such alterations in libido and sensitivity will decrease and normalize post-cycle. A transient effect may occur post-cycle, where a woman may experience a low libido until her endogenous testosterone levels recover back to normal levels (taking 1-2 weeks).

Slight Cholesterol Increase

One woman had blood tests taken pre- and post-Ostarine cycles, and although her overall health remained excellent, she noticed a small increase in cholesterol (2). To some, this may be considered a benefit, with it being an unsubstantial increase. However, women struggling with hypertension may want to use caution.

ALT/AST Enzymes

Based on our LFTs (liver function tests), liver enzymes will temporarily rise on Ostarine, causing slight hepatic inflammation (3). However, this is unlikely to be troublesome, considering Ostarine’s mild nature and the exceptional resilience of the average liver.

A typical scenario is that a woman’s ALT/AST enzymes rise modestly on-cycle and quickly fall back within a normal range post-cycle.

Ostarine Cycle for Women

  • Week 1: 7mg/day
  • Week 2: 7mg/day
  • Week 3: 10mg/day
  • Week 4: 10mg/day
  • Week 5: 10mg/day
  • Week 6: 10mg/day
  • Week 7: 10mg/day
  • Week 8: 10mg/day
  • Week 9: 10mg/day
  • Week 10: 10mg/day

The above Ostarine cycle is optimal for female beginners who have not tried Ostarine before.

Some women increase the dosage to 12 or 15 mg/day and extend the cycle to 12 weeks; however, we find the risk of side effects then increases.

Increasing the dose will depend on a woman’s tolerance, and even then, high dosages should not be implemented at the beginning of a cycle, but preferably after a few weeks (giving the body time to transition).

Typically, dosages exceeding 10 mg/day will yield minimal extra gains. Therefore, 10 mg/day is a generous dose, especially for women who purchase SARMs from companies that guarantee high purity with COAs (certificates of analysis).


Do Women Need to Take a PCT after Ostarine?

A few women may experience symptoms of endogenous suppression, such as lower mood, libido, and energy levels post-cycle. However, the extent of these side effects is only mild and, in most cases, unnoticeable.

Therefore, most women do not utilize PCT (post-cycle therapy) following an Ostarine-only cycle, as this SARM causes little suppression.

How Many Doses Do I Need to Take Per Day?

Ostarine has a half-life of 24 hours (4), so only 1 dose per day is required for optimal results. This should be taken at approximately the same time each day.

Ostarine can be taken 1 hour (or less) before a workout for enhanced strength, energy, and motivation. It works almost immediately, with women often feeling more aggressive and energetic just minutes after a dose.

Should Ostarine Be Taken With or Without Food?

SARMs, including Ostarine, can occasionally cause an upset stomach. Thus, taking SARMs with food can preserve the stomach lining.


Ostarine demonstrates remarkable anabolic properties in women, combined with a mild side-effect profile. Therefore, we consider it to be among the best PEDs for improving body composition in medicine and bodybuilding today.

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